Faculty Mentors

Lui AliceProfessor Alice Y. Liu, is interested in understanding the role protein quality control (QC) in the context of neurodegenerative disease pathogenesis and therapeutics.  The rationale and import of this work include: (1) the importance of protein QC in stress resistance and longevity, and (2) defects in protein QC contribute importantly to pathogenesis of age-related neurodegenerative diseases (ND) such as Alzheimer’s, Parkinson’s, Lou Gehrig’s, Huntington’s, and prion diseases.  Using a cell model of Huntington’s Disease (HD), her recent work showed the importance of protein QC in the aggregation and pathogenicity of the mutant Huntingtin protein (mHtt) and downstream transcription factor regulation.  As a long serving Rutgers University professor, she firmly believes in the importance of research-based teaching and learning of undergraduate students and has regularly engaged students in her research.  She enjoys teaching and interaction with students in the classroom as well as at the lab bench and works to inspire and challenge all her students to strive for their very best.  

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W https://sites.rutgers.edu/alice-liu/